Efficacy and tolerability of chondroitin sulfate 1200 mg/day vs chondroitin sulfate 3×400 mg/day vs placebo

Chondroitin sulfate

While some complementary and alternative techniques have been studied scientifically, high-quality data regarding safety, effectiveness, and mechanism of action are limited or controversial for most therapies. Whenever possible, it is recommended that practitioners be licensed by a recognized professional organization that adheres to clearly published standards. In addition, before starting a n...

Biosynthesis of Chondroitin Sulfate

A microsomal preparation from chick embryo cartilage has been shown to catalyze the incorporation of sulfate-36S from 3’-phosphoadenosine 5’-phosphosulfate-3% into microsomal glycosaminoglycan. This enzyme preparation is the same preparation that previously has been shown to catalyze the formation of chondroitin (nonsulfated) from sugar nucleotide precursors. The microsomal sulfate acceptor app...

Biosynthesis of Chondroitin Sulfate

The role of phospholipids in the activity of UDP-D-galactose:D-xylose galactosyltransferase (galactosyltransferase I) from embryonic chick cartilage was investigated. Phospholipase C treatment of particulate galactosyltransferase I caused inactivation of this enzyme to the extent of 60 to 70% as well as hydrolysis of 75 to 80% of the membrane phospholipids. Addition of phospholipid restored act...

Chondroitin Sulfate A-Adhering

Neuroactive chondroitin sulfate glycomimetics.

Journal of the American Chemical Society is published by the American Chemical Society. 1155 Sixteenth Street N.W., Washington, DC 20036 Communication Neuroactive Chondroitin Sulfate Glycomimetics Manish Rawat, Cristal I. Gama, John B. Matson, and Linda C. Hsieh-Wilson J. Am. Chem. Soc., 2008, 130 (10), 2959-2961• DOI: 10.1021/ja709993p • Publication Date (Web): 15 February 2008 Downloaded from...